Multiple Myeloma Yields To Newer Therapy Many tears ago when I was teaching residents and fellows at Manhattan's Lennox Hill Hospital there wasn't much new to teach. We had old medications including Cytoxan and other cytoxan-like medications and prednisone or dexamethasone (decadron). If patients relapsed from this therapy they were offered an autologous bone marrow transplantation after receiving very high doses of similar medications or high-doses of the old therapies without transplant. It took several years to appreciate that the transplants actually extended the survival for many patients eligible to receive such therapy. Survivability from transplantation rapidly increased when done at the transplant centers. The procedure was initiated at M.D. Anderson hospital in Houston and subsequently fame came to the state of Arkansas which rapidly became the myeloma transplant center for the USA. Now, as indicated in the accompanying schema above we have several new and v...
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