Glenn Tisman, MD Heme/Onc Blog

So a surgeon told you to cut it out because you shouldn't live with cancer living in your prostate. You listened to him and a few years later the tumor raised its ugly head as indicated by a slow elevation of the PSA blood test. Now what? Well in the old days if the PSA level at the time of recurrence was  less than 2 ng/ml most radiation therapist recommended irradiating the prostate and surrounding lymph nodes. Seemed that that was associated with a slight increase in survival.  Now we can look at two newer studies that suggest adding to this recommendation will save more lives.  Shipley ( N Engl J Med 2017;376:417-28. DOI: 10.1056/NEJMoa1607529 )     studied 760 eligible patients who had undergone surgical removal of the prostate gland and lymph nodes. At the time of surgery patients had a tumor stage of T2 (confined to the prostate but with a positive surgical margin) or T3 (with histologic extension beyond the prostatic capsule), no lymph nodes were involved with

Multiple Myeloma Yields To Newer Therapy Many tears ago when I was teaching residents and fellows at Manhattan's Lennox Hill Hospital there wasn't much new to teach. We had old medications including Cytoxan and other cytoxan-like medications and prednisone or dexamethasone (decadron). If patients relapsed from this therapy they were offered an autologous bone marrow transplantation after receiving very high doses of similar medications or high-doses of the old therapies without transplant. It took several years to appreciate that the transplants actually extended the survival for many patients eligible to receive such therapy. Survivability from transplantation rapidly increased when done at the transplant centers. The procedure was initiated at M.D. Anderson hospital in Houston and subsequently fame came to the state of Arkansas which rapidly became the myeloma transplant center for the USA. Now, as indicated in the accompanying schema above we have several new and v

Lymphoma Therapy is Rapidly Changing: Patients do your homework, you may have to become your physician's mentor.  This post reveals several of the newest effective therapies for patients with follicular lymphoma. Many of these drugs are effective for different types of lymphoma. The survival of patients is increasing while drug toxicity diminishes. Many busy physicians may not be aware of these results. Let them know! [ORR = overall response rate; CR = complete responders (absence of all measurable lymphoma); PFS = progression-free survival. Number refers to number of patients studied]. DYNAMO study results added 6/20/2017. Glenn Tisman, M.D.

glennmd@gmail.com Newest Prostate Cancer Therapy Helps Prostate Cancer Patients Live Longer.  Tell your oncologist or urologist to change to the latest therapy right now! Glenn Tisman, M.D. Hemoatology/Oncology Rancho Santa Margarita, CA USA

www.gtisman.com New Advanced Lung Cancer Therapy Recommendation as of August 4, 2017.  Treatment of lung cancer is rapidly changing almost on a week by week basis. I have put together an easy to understand flow chart/algorithm of the newest pathways leading to the most effective results as of August 4, 2017. Check out www.physiciannutritionassociates.com or www.gtisman.com for BLOGS on other cancer issues. Glenn Tisman, M.D. Hematology/Oncology Rancho Santa Margarita, CA USA

Wiley InterScience :: Journal :: Article PDF